Intravenous paracetamol and intraocular pressure reduction: mannitol may also be involved

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Intravenous paracetamol and intraocular pressure reduction: mannitol may also be involved

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The intraocular pressure-lowering properties of intravenous paracetamol

AIM The aim of this paper was to investigate the intraocular pressure (IOP)-changing properties of a single standard dose of intravenous (IV) paracetamol and compare it to that of topical timolol, oral acetazolamide, and no treatment. METHODS A prospective, randomized, investigator-blind, parallel-group study was conducted in 73 eyes of 52 subjects. Subjects received a single dose of IV parac...

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Intravenous Paracetamol and Patent Ductus Arteriosus Closure

Background: Standard medical treatments for patent ductus arteriosus (PDA) closure are, including indomethacin/ibuprofen and surgical ligation. Nowadays, a new strategy to close PDA is the use of paracetamol. The present study aimed to describe the use of intravenous (IV) paracetamol for PDA closure in neonates who present a contraindication to ibuprofen or ibuprofen failure with no possibility...

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Sodium in soluble paracetamol may be linked to raised blood pressure.

A 58 year old woman was diagnosed as having polymyalgia rheumatica in 2000. Her blood pressure was slightly raised (140/74 mm Hg). Her past medical history was otherwise unremarkable and her condition stable. She takes 5 mg prednisolone a day, up to six over the counter Panadol tablets (GlaxoSmithKline, Brentwood; 500 mg paracetamol) a day, and Calcichew D3 Forte (Shire, Basingstoke; 1.25 g cal...

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Intraocular pressure reduction and regulation system.

The IOP reduction and regulation system performs certain specific functions: it can be used to lower (or raise) IOP in a controlled way; it responds rapidly to maintain a selectable, set, minimum IOP under variable flow demands; and it reduces the rapid dynamic increases in IOP resulting from loads applied to the eye. The system has been tested and evaluated in the laboratory with a small test ...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2016

ISSN: 1177-5483

DOI: 10.2147/opth.s118752